Surfactant protein D increases phagocytosis and aggregation of pollen-allergen starch granules.

Surfactant protein D decreases pollen-induced IgE-dependent mast cell degranulation.

Mast cells play a key role in allergy and asthma. They reside at the host-environment interface and are among the first cells to make contact with inhaled microorganisms and particulate antigens. Pulmonary surfactant proteins A and D (SP-A and SP-D) function in lung host defense by enhancing microbe phagocytosis and mediating other immune cell functions, but little is known about their effects ...

Implications for Airway Inflammatory Via C-Type Lectin and Integrin Receptors: Allergen- Containing Pollen Starch Granules Alveolar Macrophages Bind and Phagocytose

Molecular Cloning and Expression of Cro s 1: an Occupational Allergen from Saffron Pollen (Crocus sativus)

Background: The cultivation of saffron is expanding through the southeast of Iran, and allergy to saffron pollen occurs in workers involved in processing this plant. We aimed to clone, sequence and express a major allergen involved in saffron pollen allergy, and to compare the recombinant with the natural allergen. Methods: The N-terminal amino acid sequence of Cro s 1, an allergen from saff...

Nonionic Surfactants (Dodecyl Maltoside and Polysorbate 20) Effect on Light induced Aggregation and Conformational Changes of Recombinant Human IFNβ_1b

Liquid protein formulations are prone to form aggregates. The effect of nonionic surfactants such as Polysorbate 20 (PS 20) and n-Dodecyl β-D-maltoside (DDM) on the prevention of aggregation and conformational changes of recombinant human IFNβ-1b (rhIFN β_1b) was explored. Polysorbate has been used in formulations of protein pharmaceuticals. There have been concerns about using PS 20 due to its...

Persian bee propolis and pollen extracts enhanced the non-specific immune response of rainbow trout (Onchorhynchus mykiss) and resistance against Aeromonas hydrophila

The effect of Persian bee propolis and pollen extracts on innate immune response of rainbow trout (Onchorhynchus mykiss) was investigated. Fish were fed diets containing 1% Pollen, 1% propolis and combination of the two immune-stimulants (0.5% Pollen and 0.5% propolis) as treatment groups and fed without the two immune-stimulants as positive and negative control groups for 4 weeks. The effects ...